Lewis Blood-group Antigens Are Associated With Altered Susceptibility to Shigellosis
نویسندگان
چکیده
منابع مشابه
Expression of blood group-related antigens ABH, Lewis A, Lewis B, Lewis X, Lewis Y, and CA 19-9 in pancreatic cancer cells in comparison with the patient's blood group type.
Blood group A, B, H, Le, Leb, Lex, and Ley antigenicity as well as the expression of CA 19-9 were examined in pancreatic cancer specimens from 30 patients, using monoclonal antibodies to the respective antigen and immunohistochemical techniques, and the findings were correlated with the blood group types (ABO and Lewis) of the individuals. Compatible antigen expression was found in 82, 75, and ...
متن کاملDifferential Tissue Expression of the Lewis Blood Group Antigens : Enzymatic , Immunohistologic , and Immunochemical Evidence for Lewis a and b Antigen
The Lewis blood group system comprises two main carbohydrate antigens, Le’ and Leb. Lewis typing has traditionally been based on serologic determinations using erythrocytes and saliva. Several recent studies have demonstrated that erythrocyte Lewis phenotype may change during pregnancy or disease, and inappropriate Lewis antigens have been found in both normal and neoplastic tissue. To evaluate...
متن کاملChanges of the expression of Lewis blood group antigens in glycoproteins of renal cancer tissues.
Sialic acid and sialyl Lewisa/x are found on N- and O-glycans of many human malignant cells. Carbohydrate antigens can be used as tumor markers, and an increase of their levels in cancer cells is associated with tumor progression. The aim of this study was to assess the level of some Lewis blood group antigens on glycoproteins in tumor (cancer tissue), intermediate zone (adjacent to tumor tissu...
متن کاملRole of the Lewis and ABO Blood Group Antigens in Helicobacter pylori Infection.
BACKGROUND Helicobacter pylori infection is a major risk factor for chronic gastritis and gastric cancer. Some findings show increased frequencies of these diseases in individuals with type O blood and in secretors (expressing Le(b) antigen), but other studies have not found any relationship between blood groups and this infection. Given that H. pylori infection and gastric cancer are common in...
متن کاملDifferential Tissue Expression of the Lewis Blood Group Antigens : Enzymatic , Immunohistologic , and Immunochemical
The Lewis blood group system comprises two main carbohydrate antigens, Le’ and Leb. Lewis typing has traditionally been based on serologic determinations using erythrocytes and saliva. Several recent studies have demonstrated that erythrocyte Lewis phenotype may change during pregnancy or disease, and inappropriate Lewis antigens have been found in both normal and neoplastic tissue. To evaluate...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2020
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciaa1409